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Frontotemporal Dementia

FTD are a group of disorders characterized by their communication deficits. Redenlab are experts in describing and tracking the many speech and language impairments caused by these conditions.

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Phase I

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Publications

Enhancing monitoring of FTD

u003cpu003eu003cspan class=u0022TextRun BCX0 SCXP226751985u0022 lang=u0022EN-USu0022 xml:lang=u0022EN-USu0022 data-scheme-color=u0022@595959,1,18:65000,19:35000u0022 data-usefontface=u0022trueu0022 data-contrast=u0022noneu0022u003eu003cspan class=u0022NormalTextRun BCX0 SCXP226751985u0022u003eThere are no FDA approved therapies for FTD, but clinical trials are underway. FTD is a group of disorders characterised by changes to behaviour, language, motor speech, and activities of daily living.u0026nbsp;u003c/spanu003eu003c/spanu003eu003c/pu003eu003cpu003eu003cspan class=u0022TextRun SCXP29965823 BCX0u0022 lang=u0022EN-USu0022 xml:lang=u0022EN-USu0022 data-scheme-color=u0022@595959,1,18:65000,19:35000u0022 data-usefontface=u0022trueu0022 data-contrast=u0022noneu0022u003eu003cspan class=u0022NormalTextRun SCXP29965823 BCX0u0022u003eRedenlab scientists are leading the field of FTD communication research. Theyu0026nbsp;u003c/spanu003eu003c/spanu003eu003cspan class=u0022TextRun SCXP29965823 BCX0u0022 lang=u0022EN-USu0022 xml:lang=u0022EN-USu0022 data-scheme-color=u0022@595959,1,18:65000,19:35000u0022 data-usefontface=u0022trueu0022 data-contrast=u0022noneu0022u003eu003cspan class=u0022NormalTextRun SCXP29965823 BCX0u0022u003epartner with global key opinion leaders across natural history studies and treatmentu0026nbsp;u003c/spanu003eu003c/spanu003eu003cspan class=u0022TextRun SCXP29965823 BCX0u0022 lang=u0022EN-USu0022 xml:lang=u0022EN-USu0022 data-scheme-color=u0022@595959,1,18:65000,19:35000u0022 data-usefontface=u0022trueu0022 data-contrast=u0022noneu0022u003eu003cspan class=u0022NormalTextRun SCXP29965823 BCX0u0022u003etrials. Communication is adversely impacted across all FTD phenotypes making itu0026nbsp;u003c/spanu003eu003c/spanu003eu003cspan class=u0022TextRun SCXP29965823 BCX0u0022 lang=u0022EN-USu0022 xml:lang=u0022EN-USu0022 data-scheme-color=u0022@595959,1,18:65000,19:35000u0022 data-usefontface=u0022trueu0022 data-contrast=u0022noneu0022u003eu003cspan class=u0022NormalTextRun SCXP29965823 BCX0u0022u003ean ideal marker of quality of life and overall disease function.u0026nbsp;u003c/spanu003eu003c/spanu003eu003c/pu003e

people sitting on chair in front of computer monitor

Differentiate FTD from other diseases​

u003cpu003eu003cspan class=u0022TextRun SCXP147827131 BCX0u0022 lang=u0022EN-USu0022 xml:lang=u0022EN-USu0022 data-scheme-color=u0022@FFFFFF,0,u0022 data-usefontface=u0022trueu0022 data-contrast=u0022noneu0022u003eu003cspan class=u0022NormalTextRun SCXP147827131 BCX0u0022u003eThe diagnostic journey for people with FTD can be long. Theu0026nbsp;u003c/spanu003eu003c/spanu003eu003cspan class=u0022TextRun SCXP147827131 BCX0u0022 lang=u0022EN-USu0022 xml:lang=u0022EN-USu0022 data-scheme-color=u0022@FFFFFF,0,u0022 data-usefontface=u0022trueu0022 data-contrast=u0022noneu0022u003eu003cspan class=u0022NormalTextRun SCXP147827131 BCX0u0022u003eFTD disease profile can beu0026nbsp;u003c/spanu003eu003c/spanu003eu003cspan class=u0022TextRun SCXP147827131 BCX0u0022 lang=u0022EN-USu0022 xml:lang=u0022EN-USu0022 data-scheme-color=u0022@FFFFFF,0,u0022 data-usefontface=u0022trueu0022 data-contrast=u0022noneu0022u003eu003cspan class=u0022NormalTextRun SCXP147827131 BCX0u0022u003econfused withu0026nbsp;u003c/spanu003eu003c/spanu003eu003cspan class=u0022TextRun SCXP147827131 BCX0u0022 lang=u0022EN-USu0022 xml:lang=u0022EN-USu0022 data-scheme-color=u0022@FFFFFF,0,u0022 data-usefontface=u0022trueu0022 data-contrast=u0022noneu0022u003eu003cspan class=u0022NormalTextRun SCXP147827131 BCX0u0022u003eother diseases suchu0026nbsp;u003c/spanu003eu003c/spanu003eu003cspan class=u0022TextRun SCXP147827131 BCX0u0022 lang=u0022EN-USu0022 xml:lang=u0022EN-USu0022 data-scheme-color=u0022@FFFFFF,0,u0022 data-usefontface=u0022trueu0022 data-contrast=u0022noneu0022u003eu003cspan class=u0022NormalTextRun SCXP147827131 BCX0u0022u003eas Alzheimeru0026rsquo;s and other forms of dementia, with almost 40% ofu0026nbsp;u003c/spanu003eu003c/spanu003eu003cspan class=u0022TextRun SCXP147827131 BCX0u0022 lang=u0022EN-USu0022 xml:lang=u0022EN-USu0022 data-scheme-color=u0022@FFFFFF,0,u0022 data-usefontface=u0022trueu0022 data-contrast=u0022noneu0022u003eu003cspan class=u0022NormalTextRun SCXP147827131 BCX0u0022u003epatients initially misdiagnosed. The unique speech and languageu0026nbsp;u003c/spanu003eu003c/spanu003eu003cspan class=u0022TextRun SCXP147827131 BCX0u0022 lang=u0022EN-USu0022 xml:lang=u0022EN-USu0022 data-scheme-color=u0022@FFFFFF,0,u0022 data-usefontface=u0022trueu0022 data-contrast=u0022noneu0022u003eu003cspan class=u0022NormalTextRun SCXP147827131 BCX0u0022u003ephenotypes within the FTD spectrum means communication canu0026nbsp;u003c/spanu003eu003c/spanu003eu003cspan class=u0022TextRun SCXP147827131 BCX0u0022 lang=u0022EN-USu0022 xml:lang=u0022EN-USu0022 data-scheme-color=u0022@FFFFFF,0,u0022 data-usefontface=u0022trueu0022 data-contrast=u0022noneu0022u003eu003cspan class=u0022NormalTextRun SCXP147827131 BCX0u0022u003ebe used to assist in differential diagnosis.u003c/spanu003eu003c/spanu003eu003c/pu003e

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Manage your FTD trials with ease​

u003cpu003eu003cspan class=u0022TextRun SCXP211242236 BCX0u0022 lang=u0022EN-USu0022 xml:lang=u0022EN-USu0022 data-scheme-color=u0022@FFFFFF,0,u0022 data-usefontface=u0022trueu0022 data-contrast=u0022noneu0022u003eu003cspan class=u0022NormalTextRun SCXP211242236 BCX0u0022u003eRedenlab offers a suite of management tools to assess, validateu0026nbsp;u003c/spanu003eu003c/spanu003eu003cspan class=u0022TextRun SCXP211242236 BCX0u0022 lang=u0022EN-USu0022 xml:lang=u0022EN-USu0022 data-scheme-color=u0022@FFFFFF,0,u0022 data-usefontface=u0022trueu0022 data-contrast=u0022noneu0022u003eu003cspan class=u0022NormalTextRun SCXP211242236 BCX0u0022u003eand analyse FTD studies across more than 100 sites globally.u0026nbsp;u003c/spanu003eu003c/spanu003eu003cspan class=u0022TextRun SCXP211242236 BCX0u0022 lang=u0022EN-USu0022 xml:lang=u0022EN-USu0022 data-scheme-color=u0022@FFFFFF,0,u0022 data-usefontface=u0022trueu0022 data-contrast=u0022noneu0022u003eu003cspan class=u0022NormalTextRun SCXP211242236 BCX0u0022u003eRedenlabu0026rsquo;s objective markers of speech and language are beingu0026nbsp;u003c/spanu003eu003c/spanu003eu003cspan class=u0022TextRun SCXP211242236 BCX0u0022 lang=u0022EN-USu0022 xml:lang=u0022EN-USu0022 data-scheme-color=u0022@FFFFFF,0,u0022 data-usefontface=u0022trueu0022 data-contrast=u0022noneu0022u003eu003cspan class=u0022NormalTextRun SCXP211242236 BCX0u0022u003eused to monitor changes in patient performance, enhancingu0026nbsp;u003c/spanu003eu003c/spanu003eu003cspan class=u0022TextRun SCXP211242236 BCX0u0022 lang=u0022EN-USu0022 xml:lang=u0022EN-USu0022 data-scheme-color=u0022@FFFFFF,0,u0022 data-usefontface=u0022trueu0022 data-contrast=u0022noneu0022u003eu003cspan class=u0022NormalTextRun SCXP211242236 BCX0u0022u003etherapeutic development decisions in your next clinical trial.u003c/spanu003eu003c/spanu003eu003c/pu003e

Abstract green wavy pattern on black background

Leading analytics among leading academics​

u003cpu003eu003cspan class=u0022TextRun BCX0 SCXP12662225u0022 lang=u0022EN-USu0022 xml:lang=u0022EN-USu0022 data-scheme-color=u0022@595959,1,18:65000,19:35000u0022 data-usefontface=u0022trueu0022 data-contrast=u0022noneu0022u003eu003cspan class=u0022NormalTextRun BCX0 SCXP12662225u0022u003eRedenlab partners with the world leading clinician researchers in FTD. Partnerships include:u003c/spanu003eu003c/spanu003eu003c/pu003eu003culu003eu003cli data-charcodes=u00228226u0022 data-font=u0022Arial,Sans-Serifu0022 data-buautonum=u00228u0022 data-margin=u0022270u0022 data-aria-posinset=u00221u0022 data-aria-level=u00221u0022u003eu003cspan data-scheme-color=u0022@595959,1,18:65000,19:35000u0022 data-usefontface=u0022trueu0022 data-contrast=u0022noneu0022u003eMemory and Aging Center u0026ndash; UCSF, USAu003c/spanu003e​u003c/liu003eu003cli data-charcodes=u00228226u0022 data-font=u0022Arial,Sans-Serifu0022 data-buautonum=u00228u0022 data-margin=u0022270u0022 data-aria-posinset=u00222u0022 data-aria-level=u00221u0022u003eu003cspan data-scheme-color=u0022@595959,1,18:65000,19:35000u0022 data-usefontface=u0022trueu0022 data-contrast=u0022noneu0022u003eUCL Queen Square Institute of Neurology, UKu003c/spanu003e​u003c/liu003eu003cli data-charcodes=u00228226u0022 data-font=u0022Arial,Sans-Serifu0022 data-buautonum=u00228u0022 data-margin=u0022270u0022 data-aria-posinset=u00223u0022 data-aria-level=u00221u0022u003eu003cspan data-scheme-color=u0022@595959,1,18:65000,19:35000u0022 data-usefontface=u0022trueu0022 data-contrast=u0022noneu0022u003eEastern Cognitive Disorders Clinic, Melbourne, Australiau003c/spanu003e​u003c/liu003eu003cli data-charcodes=u00228226u0022 data-font=u0022Arial,Sans-Serifu0022 data-buautonum=u00228u0022 data-margin=u0022270u0022 data-aria-posinset=u00224u0022 data-aria-level=u00221u0022u003eu003cspan data-scheme-color=u0022@595959,1,18:65000,19:35000u0022 data-usefontface=u0022trueu0022 data-contrast=u0022noneu0022u003eThe University of Melbourne, Australiau003c/spanu003e​u003c/liu003eu003cli data-charcodes=u00228226u0022 data-font=u0022Arial,Sans-Serifu0022 data-buautonum=u00228u0022 data-margin=u0022270u0022 data-aria-posinset=u00225u0022 data-aria-level=u00221u0022u003eu003cspan data-scheme-color=u0022@595959,1,18:65000,19:35000u0022 data-usefontface=u0022trueu0022 data-contrast=u0022noneu0022u003eUniversity of Texas in Austin, USAu003c/spanu003eu003c/liu003eu003c/ulu003e

Use cases for communication monitoring in FTD​

Post marketing​

CNS health

Communication related quality of life

Treatment efficacy

Further reading

Mealtime difficulties following frontotemporal lobar degeneration

BACKGROUND: Frontotemporal lobar degeneration (FTLD) can result in a decline in behavior, language, and motor function. Mealtime disturbances are a common and significant outcome of…
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Motor speech signature of behavioral variant frontotemporal dementia: Refining the phenotype

Comprehensive description of motor speech function in behavioral variant frontotemporal dementia (bvFTD) One in 8 patients presented with moderate speech timing deficits with a further…
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Motor speech phenotypes of frontotemporal dementia, primary progressive aphasia, and progressive apraxia of speech

Measures of speech which can assist with diagnosis and classification in FTD, PPA, and progressive apraxia of speech.   Click here for more details.
Read more

For more information

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